Addiction Medicine Boards Practice Test

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• How does nicotine affect the metabolism of antipsychotic medications?
• What is the starting dose of bupropion for smoking cessation?
• What strength of nicotine gum should a patient use if they smoke their first cigarette within 30 minutes of waking?
• What type of disorder is most likely to complicate the treatment of substance use disorders?
• Where do Z-drugs primarily bind in the brain?
• Patients using PCP display very specific symptoms including what type of nystagmus?
• Which enzyme converts alcohol to acetaldehyde?
• In terms of recovery from substance use disorders, how do court-mandated IOP and voluntary IOP participants compare?
• What eating disorder was introduced in the DSM-5?
• What is the primary enzyme involved in the first step of cocaine metabolism?
• What did the Monitoring the Future (MTF) survey show regarding marijuana trends in 2019?
• What type of receptor is CB1?
• True or false: An unintentional opioid overdose from prescribed opioids for chronic pain is a risk factor for repeat overdose.
• What action do alcohol molecules primarily take at the GABA-A receptor?
• What modified Finnegan score typically indicates the need for medication?
• What is the formula for calculating absolute risk?
• Do hallucinogens typically cause withdrawal symptoms or physical dependence?
• Which demographic factors are associated with a lower prevalence of substance use disorders?
• What notable exception exists for hallucinogens regarding withdrawal and dependence?
• Who is required to report substance use disorders per FAA regulations?
• How is sensitivity defined in the context of a medical test?
• Which syndrome cannot be definitively diagnosed in children younger than three years old?
• Which of the following statements about nicotine replacement therapies is true?
• What metabolite is specifically expected for hydromorphone on confirmatory urine testing?
• What is the primary characteristic of zero-order kinetics in alcohol metabolism?
• Which drug is known to cause a false positive for PCP on a urine drug screen?
• Which metabolic condition is a risk factor for faster progression of hepatitis C to cirrhosis?
• What is the subsequent product after acetaldehyde is metabolized?
• What does Hallucinogen Persisting Perceptual Disorder involve?
• What is synthetic cannabis known for in terms of its receptor affinity?
• Which substance can sometimes lead to missed detection in standard urine drug screens?
• What synthetic drug is often associated with agitation, tachycardia, and psychosis without stimulant traces in urine tests?
• Which dietary supplement combined with contingency management has shown to reduce cannabis use?
• What percentage of 12th graders vaped marijuana daily?
• Which outcome is likely to be worsened by the co-occurrence of personality disorders and substance use disorders?
• What is a significant risk associated with substance use disorders in the presence of personality disorders?
• What schedule classification is buprenorphine categorized under?
• Which neurotransmitter systems are primarily affected by amphetamines?
• What is the most common side effect of varenicline?
• Which type of drug is mephedrone categorized as?
• What is the average detection time for PCP in a urine immunoassay?
• What is the relationship between heavy use of cannabis and detection window in urine tests?
• What effect does St. John’s wort have on methadone levels?
• What factor is critical for the effectiveness of opioid use disorder treatment in adolescents?
• Which neurotransmitter is not typically associated with the reuptake actions of cocaine?
• Which brain area is involved in craving during the preoccupation/anticipation phase of addiction?
• What has largely contributed to the upward trend in drug use reported?
• What is the formula for calculating NPV?
• What is the primary action of cocaine in relation to neurotransmitter reuptake?
• Which factor presents a higher risk for substance use disorder?
• Which of the following statements about prenatal alcohol exposure is false?
• Which benzodiazepine is not commonly detected in urine drug screens?
• Which autonomic disturbance is a sign of NOWS?
• How is binge drinking defined in terms of Blood Alcohol Level (BAL)?
• Which substance can cause a false positive for methamphetamine in a urine drug screen?
• Within how many days of life can NOWS onset occur with the use of buprenorphine or methadone?
• What is the peak concentration time for buprenorphine in the body?
• What does the USPSTF recommend for individuals aged 55-80 with a significant smoking history?
• Which of the following is a common gastrointestinal disturbance seen in NOWS?
• What does therapeutic jurisprudence refer to?
• What kind of agonist is synthetic cannabis at the CB1 receptor?
• What receptor/NT imbalance characterizes benzodiazepine withdrawal?
• On which type of receptor does nicotine primarily act?
• At what BAL does anesthesia typically occur?
• Which benzodiazepine is preferred for treating alcohol withdrawal in patients with cirrhosis?
• Which of the following is a potential adverse effect of smoking during pregnancy?
• What aspect of treatment is often hindered by the presence of personality disorders in individuals with substance use disorders?
• What is a notable challenge in treating substance use disorders for individuals with personality disorders?
• What is the potential effect of cannabis use during pregnancy?
• Which enzyme is responsible for metabolizing buprenorphine to norbuprenorphine?
• What is considered a highly sensitive test's key characteristic?
• How do personality disorders typically affect treatment engagement in individuals with substance use disorders?
• What can develop rapidly with the repeated use of hallucinogens?
• What is a key function of the CB2 receptor?
• What is the structure of the GABA-A receptor?
• Is prescription opioid drug use among youth increasing or decreasing?
• Which of the following is a common impact of personality disorders on individuals undergoing substance use disorder treatment?
• Which medication has been shown to help with cannabis use disorder in adolescents?
• What is meant by delay discounting in the context of addiction?
• Which mental health disorders are associated with increased adolescent drug use?
• Who is most commonly affected by gambling disorder?
• Which receptor does Delta 9 THC partially activate?
• What is the 12-month prevalence for non-alcohol drug substance use disorder?
• What do endorphins, enkephalins, dynorphins, and endomorphins collectively bind to?
• What was the primary goal of the Comprehensive Addiction and Recovery Act (CARA) of 2016?
• Which combination is considered the most effective for school-based prevention programs for adolescent substance use?
• What neurotransmitter receptor do hallucinogens primarily target?
• Which organization is responsible for overseeing substance use disorder reporting in pilots?
• Ibogaine has different effects depending on the dosage. What is its effect at higher doses?
• What happens to the efficacy of antipsychotic medications when a patient starts smoking regularly?
• What is the 12-month prevalence of Alcohol Use Disorder (AUD)?
• What is the potential consequence of combining methadone with CYP3A4 inducers?
• Which FDA-approved product is used for seizures greater than 2 years old due to specific syndromes?
• What is the typical detection time for cannabis after use of a single joint?
• What is the formula for relative risk reduction?
• What did the MOTHER study primarily investigate?
• Which of the following is a major side effect of disulfiram?
• What is the most commonly used hallucinogen in the United States?
• What type of kinetics is alcohol metabolism characterized by?
• What effect does fluconazole have when given to someone on methadone?
• What treatment-level factors are associated with better prognosis for adolescents with substance use disorders (SUDs)?
• Which psychiatric symptom is commonly associated with disulfiram use?
• At what rate do alcohol levels typically fall during metabolism?
• What type of drug is Nitrous Oxide classified as?
• What effect do personality disorders have on motivation for treatment among individuals with substance use disorders?
• What effect does bupropion have in addition to being an NE and dopamine reuptake inhibitor?
• Which test is considered the most accurate for assessing nicotine dependence?
• What age group does the NSDUH survey cover for measuring drug use?
• What is a suggested treatment for Hallucinogen Persisting Perceptual Disorder?
• Opioids primarily bind to which type of receptors?
• What is the first-line treatment approach for tobacco use disorder in pregnant individuals?
• What type of therapy is Multidimensional Family Therapy considered to be?
• What is the primary mechanism of action of varenicline in treating tobacco use disorder?
• Which of the following is a possible symptom during cannabis withdrawal?
• What is the first-line treatment option for gambling disorder?
• What is the risk percentage of dependence for adult cannabis users?
• How long can cannabis be detected in a urine immunoassay for heavy users?
• What is DMT primarily associated with?
• Do positive predictive value (PPV) and negative predictive value (NPV) change with prevalence?
• Which of the following is NOT one of the FDA approved forms of Nicotine Replacement Therapy?
• Which receptor is antagonized by ethanol and is implicated in learning and memory?
• PCP is categorized as what type of drug?
• Which of the following criteria is required to define Alcohol-Related Birth Defects?
• Which metabolites are expected for oxycodone on confirmatory urine testing?
• What is a potential effect of cocaine use during pregnancy?
• What percentage of 12th graders reported daily use of nicotine vaping in the past month?
• Which approach is recommended for all infants experiencing NOWS?
• What cotinine level indicates recent use of cigarettes after smoking a single cigarette?
• What is a key action to take if you suspect a pharmacist is involved in unethical practices regarding controlled substances?
• What is the number needed to treat (NNT) for oral naltrexone to prevent heavy drinking?
• How do efavirenz and nevirapine affect methadone levels?
• Which treatment is identified as the most effective for smokeless tobacco use?
• How do erythromycin, clarithromycin, and ciprofloxacin affect methadone levels?
• Which of the following is NOT a feature of Fetal Alcohol Syndrome (FAS)?
• What is the definition of positive predictive value (PPV)?
• What is the primary enzyme that metabolizes methadone?
• How long do stimulants typically remain detectable in a urine immunoassay?
• Which of the following approaches is recommended for treating tobacco use disorder?
• What is one potential advantage when treating substance use disorders without the presence of personality disorders?
• What is the typical detection window for short-acting opioids in a urine immunoassay?
• Where is the CB1 receptor predominantly expressed?
• What does specificity refer to in diagnostic testing?
• What are the expected metabolites for codeine on confirmatory urine testing?
• What schedule classification do Z-drugs fall under?
• What is the "tripling effect" related to tobacco use disorder treatment?
• What percentage of smokers are successful in quitting unaided after attempting to quit each year?
• What BAL range is considered to begin alcohol coma?
• What is the calculation method for determining the number needed to treat (NNT)?
• Which factors are associated with increased rates of hepatitis C progression to cirrhosis?
• Which agency regulation applies to facilities providing substance use disorder (SUD) treatment and receiving federal funding?
• In what year was methadone officially permitted for the treatment of opioid use disorder (OUD) in the United States?
• What is Khat primarily known for?
• Which mental disorder is most commonly associated with Substance Use Disorder?
• How is the best effect from the nicotine inhaler achieved?
• What is the role of the room-in approach in NOWS management?
• Which metabolites are expected for morphine on confirmatory urine testing?
• What is the aim of primary prevention in the context of disease management?
• Individuals with personality disorders and substance use disorders often experience what outcome related to treatment?
• What is the typical onset time of Neonatal Opioid Withdrawal Syndrome (NOWS) in a pregnant person who uses heroin?
• What is a key characteristic of the alpha4beta2 nAChR receptor in relation to addiction?
• Is cannabis withdrawal syndrome recognized by DSM-5?
• Which type of receptor do dissociatives primarily act upon?
• If a pharmacist is suspected of shorting patients on controlled substances, what should you do?
• Why is critical evaluation of advertising important in prevention programs?
• What was the purpose of the DATA 2000 legislation?
• Which two side effects are particularly prevalent in tramadol use?
• Which metabolites can be expected for hydrocodone on confirmatory urine testing?
• Which age group typically shows a higher risk for alcohol-related problems?
• What effect does smoking have on fetal growth?
• When is it generally advised to stop treatment for tobacco use disorder?
• What is Salvia Divinorum known for causing?
• What is commonly understood about those who attend court-mandated IOP compared to voluntary IOP participants?
• Which medications for alcohol use disorder (AUD) have been studied in adolescents?
• What is the main focus of SAMHSA as related to NSDUH?
• According to the NSDUH 2018 tobacco trends, what is the general trend in tobacco use?
• What is a reliable test to detect recent THC use?
• True or False: Benzodiazepines increase the frequency of chloride channel opening after binding to the GABA receptor.
• Do sensitivity and specificity change with prevalence of the disease?
• What is a well-known serious risk of inhalant use?
• What are common signs of Neonatal Opioid Withdrawal Syndrome (NOWS)?
• Is internet addiction officially classified in the DSM-5?
• What is a significant risk associated with the use of mephedrone and alpha-PVP?
• How is absolute risk reduction calculated?
• What is an important consideration when prescribing varenicline?
• Where do benzodiazepines (benzos) bind on the GABA-A receptor?
• Which medication should be avoided in treating Hallucinogen Persisting Perceptual Disorder?
• What is the impact of psychological drugs that induce CYP3A4 on opioid patients?
• What is one of the main metabolites of alcohol produced via ADH?
• Which of the following is NOT a characteristic of hallucinogens?
• What is the impact of smoking on neurodevelopmental outcomes in children?
• Which substance use disorder is tobacco most closely linked to?
• What is the purpose of normative education in substance use prevention?
• What is the mechanism of action for Flumazenil?
• What medication requires special criteria for adolescents aged 16-18 and must be accompanied by a signed FDA consent form?
• What is "spice" commonly referred to?
• What is a key characteristic of binge eating disorder?
• What is a potential consequence of abrupt benzodiazepine withdrawal?
• Which group of medications has shown limited effectiveness for adolescents compared to adults?
• What key framework did the Controlled Substances Act establish in 1970?
• What is the minimum number of criteria needed to diagnose gambling disorder?
• Which medication has shown efficacy for cannabis use disorder in adults?
• What is one of the major effects of MDMA?
• Which drug is associated with symptoms like psychosis to coma, alongside specific nystagmus?
• Which new eating disorder was recognized in the DSM-5?
• What is the recommended dosing schedule for varenicline?
• What trend has been observed regarding Adderall use in teens?
• What is one feature that effective school-based prevention programs should have?
• Which enzyme is primarily responsible for the metabolism of nicotine in the body?
• Which three mental illnesses are most commonly associated with smoking behaviors?
• What is the percentage of adolescent cannabis users at risk of developing dependence?
• How do personality disorders typically influence the risk of relapse in substance use disorders?
• What product does cocaine primarily metabolize to in the liver?
• For patients smoking more than 10 cigarettes per day, what is the initial dosing recommendation for the nicotine patch?
• How many standard drinks are in a fifth of liquor?
• What action does cocaine perform besides reuptake inhibition of neurotransmitters?
• What does the National Survey on Drug Use and Health (NSDUH) assess?
• What types of receptors does mitragynine, the principal psychoactive compound in kratom, primarily bind to?
• What trend is observed in alcohol use among adolescents?
• Which of the following is NOT a treatment-level factor associated with better prognosis for adolescents with SUDs?
• What is a potential effect of smoking during pregnancy?
• How does competence enhancement benefit individuals dealing with substance use?
• According to racial patterns, which group has the highest prevalence of substance use disorders?
• What are the effects of carbamazepine, phenobarbital, and phenytoin on methadone when taken simultaneously?
• Is nicotine replacement therapy (NRT) approved for individuals under 18 years of age?
• In competence enhancement, what skills are primarily taught?
• For patients smoking 10 or fewer cigarettes per day, what is the initial dosing for the nicotine patch?
• What is the primary mechanism of action for synthetic cannabinoids?
• What percentage of 12th graders reported using any illicit drug in the past year?
• What neurotransmitter is primarily involved in the euphoria experienced during substance use in the binge/intoxication phase?
• How does MDMA differ from other hallucinogens?
• What is true about CBD in relation to CB1 and CB2 receptors?
• What condition must be excluded when diagnosing gambling disorder?
• What is the recommended dosage of nicotine lozenges for patients smoking within 30 minutes of waking?
• What trend has been observed regarding adolescent illicit drug use?
• What is the overall effect of CYP3A4 inhibitors on methadone serum levels?
• What type of receptor does PCP act as an antagonist on?
• Which smoking-related biomarker remains elevated for weeks after smoking but does not indicate low-level smoking accurately?
• What is the effect of rifampin on methadone metabolism?
• What common substance can produce a false positive for amphetamines on a urine drug screen?
• What is the alcohol blood level (BAL) at which neuro impairment begins?
• What is a common limitation of prevalence when interpreting PPV?
• What was the intent of the Pure Food and Drug Act enacted in 1906?
• What is a key factor for improving the success rate of tobacco use disorder treatment?
• Which treatment combination is considered the most effective for tobacco use disorder?
• How long does methadone remain detectable in a urine immunoassay?
• In what year was the Harrison Act enacted and what was its main purpose?
• What is the expected metabolite for heroin on confirmatory testing?
• What medication can assist with cannabis withdrawal?
• What is the prevalence of at-risk drinking for women in terms of weekly consumption?
• Which of the following is a common route of administration for mephedrone?
• Which synthetic stimulant is known for being a component of "bath salts"?
• What should comprehensive drug prevention programs include to be most effective?
• In the context of tobacco use disorder, what is the role of behavioral therapy?
• What is a feature of a highly specific test?
• Which medication is indicated to stimulate appetite in patients undergoing chemotherapy?
• In women, what is defined as at-risk drinking?
• How do personality disorders impact the overall prognosis of individuals with substance use disorders?
• Which of the following is a postnatal effect of smoking during pregnancy?
• Which receptors does methadone act on?
• What is the odds ratio for Substance Use Disorder (SUD) in individuals with bipolar disorder?
• What clinical effect does the NMDA antagonist property of methadone have?
• What is the mechanism of action of hallucinogens at receptors?
• What is the typical BAL range that is considered fatal?
• Which neurotransmitter system is primarily activated during the negative affect withdrawal phase of addiction?
• Which two benzodiazepines are known to have metabolites of nordiazepam and oxazepam?
• What may assist in mitigating the impact of personality disorders on substance use treatment outcomes?
• True or False: A person with a reduced function variant of CYP2A6 is likely to smoke more cigarettes.
• When does cannabis withdrawal typically begin?
• What does normative education in drug prevention typically promote?
• What factor contributes to a more rapid progression of gambling disorder in women?
• What is the purpose of a tapering off strategy in nicotine replacement therapies?
• Which condition is NOT typically associated with smoking or nicotine use?
• What role does Delta 9 THC play at the CB1 receptor?
• What is a key medication used to treat opioid use disorder (OUD) in adolescents?
• Which behavioral disorder is classified under Substance Use Disorders (SUD) in the DSM?
• What is the effect of grapefruit juice on methadone serum levels?
• What is one of the criteria for diagnosing gambling disorder according to DSM-5?
• Dextromethorphan has properties of which types of drugs?
• In terms of lifetime prevalence, what percentage of individuals are affected by Alcohol Use Disorder?
• Which mental disorder has the least strong association with Substance Use Disorder?
• Which of the following may be a consequence of personality disorders in the context of substance use treatment?
• What does secondary prevention focus on in disease management?
• What type of intoxication can synthetic cannabinoids resemble?
• What percentage of individuals aged 12 and older reported drug use according to the NSDUH?
• Which enzyme is also involved in alcohol metabolism and is increased with chronic use?
• What might be a consequence of falling under the influence of normative education?
• What are the names of two endogenous cannabinoids?
• What does the American Academy of Pediatrics (AAP) recommend regarding observation for NOWS?
• Which of the following treatment approaches for adolescents has the most evidence to support its effectiveness?
• What is the most common personality disorder found in individuals with Substance Use Disorders?
• What is the primary mechanism of action of GHB?
• Which of the following symptoms is NOT part of cannabis withdrawal syndrome?
• Which schedule classification do benzodiazepines belong to?
• How do benzodiazepines act on GABA receptors?
• What is a unique feature of methamphetamine's action compared to cocaine?
• Which of the following drugs is known to induce CYP3A4 and could lower methadone levels?
• What is a significant clinical implication of having a personality disorder while treating a substance use disorder?
• What type of drug is Ketamine classified as?
• What emerging biomarker is associated with alcohol withdrawal seizures?
• Which of the following is NOT a characteristic facial feature of FAS?
• Which of the following is NOT a biomarker for smoking detection?
• What is one secondary enzyme that metabolizes cocaine?
• What complication is cocaine use during pregnancy most likely associated with?
• Which side effect is commonly associated with bupropion?
• What major cardiac risk is associated with the use of ibogaine?
• How long can heavy cannabis use indicate a positive result on a urine immunoassay?
• Which of the following scenarios would require a facility to comply with 42 CFR part 2?
• Is caffeine use disorder included in the DSM?
• What cotinine level typically indicates regular cigarette use?
• What is a key component of the social resistance skills approach in preventing adolescent drug use?
• What substance is formed when cocaine is mixed with alcohol?
• What is a significant outcome of inhalant abuse?
• What condition is characterized by documented prenatal alcohol exposure and neurobehavioral impairment?
• What is the maximum number of cartridges that can be used with a nicotine inhaler per day?
• Which receptor is an agonist affected by ethanol?
• How does alcohol affect NMDA glutamate receptor function?
• What are immediate and long-term complications associated with inhalants?
• What does negative predictive value (NPV) measure in a diagnostic test?
• What is the focus of tertiary prevention?
• What factor differentiates the risk for substance use disorder according to family background?
• Which of the following statements about GABA receptors is true?
• Which neurotransmitter is most closely related to the effects of hallucinogens?
• What type of drug is mescaline/peyote classified as?
• Mephedrone and alpha-PVP are classified under which type of drug?
• Among the following, which is NOT a symptom of substance withdrawal seizures?
• What differentiates Alcohol-Related Neurodevelopmental Disorder (ARND) from Fetal Alcohol Syndrome (FAS)?
• What medications are most commonly used for treating NOWS?
• What does relative risk represent?
• What are tramadol's two specific side effects compared to other opioids?
• Which drug is classified as a cathinone and is often referred to as bath salts?
• How many cartridges of nicotine inhaler should a patient use daily during the first few weeks of treatment?
• In men, what is defined as at-risk drinking?
• Secondhand smoke exposure during pregnancy is associated with which outcome?
• What is the common duration for the detection of long-acting opioids in urine?
• Which hallucinogen is primarily used in traditional Native American ceremonies?
• What is a key characteristic of benzodiazepine dependence?
• What physiological effect does smoking have that might help alleviate symptoms of depression?
• What is the typical focus of care in the eat/sleep/console/room-in approach?
• Which enzyme is primarily responsible for nicotine metabolism?
• What is a notable characteristic of K2 compared to natural cannabis?
• What is the mechanism of action for bupropion?