Which metabolites are expected for morphine on confirmatory urine testing?

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On confirmatory urine testing for morphine, the expected metabolites that are commonly identified are morphine itself and codeine. Morphine is a primary metabolite of morphine that would be detected in the urine after morphine is ingested. Codeine, while structurally related, is also a part of the metabolic pathways and can be converted into morphine in the body, meaning its presence is consistent with morphine use, especially in cases where there is a higher intake or if codeine was used as well.

This selection aligns with the metabolic profile of morphine and its pharmacological actions. The presence of both morphine and codeine on a confirmatory test indicates a valid detection of morphine use, as morphine can be derived from codeine and is a direct product of morphine consumption.

Other combinations, such as hydrocodone or hydromorphone, do not typically result from morphine metabolism and would not be expected in a confirmatory test focused specifically on morphine. Therefore, the identification of morphine alongside codeine clearly indicates the drug's presence and its legitimate use or abuse in the context of addiction medicine.

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