Ibogaine has different effects depending on the dosage. What is its effect at higher doses?

At higher doses, ibogaine is known to produce hallucinogenic effects. This attribute is primarily due to its interaction with various neurotransmitter systems in the brain, particularly the serotonin and NMDA receptors, which can lead to altered states of consciousness and perceptual changes. Users often experience visual and auditory hallucinations as part of the drug's psychotropic properties.

In therapeutic contexts, especially when used for treating substance use disorders, these hallucinogenic effects can lead to introspective experiences that some individuals find beneficial for understanding and addressing their addiction. The experience can contribute to a type of psychotherapy that helps with emotional and psychological healing, making higher doses significant in certain treatment modalities.

The other choices, although they may represent potential effects of substances, do not align with the known pharmacological profile of ibogaine at higher doses. For instance, stimulant-like effects are more characteristic of drugs that increase norepinephrine and dopamine transmission, while relaxation and sedation are typically related to depressants. Analgesic effects may be present in certain contexts but are not a defining characteristic of ibogaine, especially at higher doses where hallucinogenic effects dominate.