Do hallucinogens typically cause withdrawal symptoms or physical dependence?

Hallucinogens, which include substances such as LSD, psilocybin, and mescaline, are primarily characterized by their capacity to alter perception, cognition, and mood. Unlike many substances associated with substance use disorders, hallucinogens typically do not result in physical dependence or withdrawal symptoms. This is largely due to the way these substances interact with the brain's neurotransmitter systems; they primarily affect serotonin receptors rather than creating a push towards compulsive use driven by withdrawal avoidance, which is common in drugs that create physical dependence.

While individuals may experience psychological effects or "bad trips," these do not equate to withdrawal symptoms comparable to those seen with substances like opioids or alcohol. Overall, the unique properties of hallucinogens lead to a classification as drugs that do not typically involve withdrawal symptoms or physical dependence, supporting the assertion that they do not cause such issues.