Which medication has been shown to help with cannabis use disorder in adolescents?

N-acetylcysteine (NAC) has shown promise in helping with cannabis use disorder, particularly in adolescents. Research indicates that NAC may help modulate the glutamatergic system, which can be disrupted by cannabis use. By restoring this balance, NAC can potentially reduce cravings and withdrawal symptoms associated with cannabis use.

Several studies have demonstrated that NAC is particularly effective in decreasing cannabis use and improving psychosocial functioning in adolescents. Its safety profile and low potential for abuse make it a suitable option for younger individuals dealing with substance use issues.

Other options may have their own therapeutic roles in various disorders, but they do not have the same level of clinical evidence supporting their use specifically for cannabis use disorder in adolescents. This makes N-acetylcysteine a unique and valuable treatment option in this context.